《惡魔獵人5》在通關劇情之後並沒有完全結束，它的血宮模式才是本作的精髓所在，在流程中熟悉玩法並解鎖完武器技能之後便可通過血宮來磨練操作技巧。以下為《惡魔獵人5》血宮模式每層怪物配置介紹。

每10層會有額外的獎勵。每5分鐘會增加0.5%的紅魂獲取（100分鐘上限，此時為2倍的紅魂收集）。

Human

Stage 1：Empusa x4

Stage 2：Green Empusa x4

Stage 3：Pyrobat x2

Stage 4：Caina x3

Stage 5：Death Scissors x1

Devil Hunter

Stage 6：Scudo x2

Stage 7：Baphomet x2

Stage 8：Riot x3

Stage 9：Qliphot tentacles x2

Stage 10 （5k bonus）：Empusa x10；Queen x1；Green x4

Stage 11：Antenora x3

Stage 12：Chaos x2

Stage 13：Proto x1

Stage 14：Lusachia x1

Stage 15：Behemoth x1

Stage 16：Hellbat x1

Stage 17：Nobody x2

Stage 18：Fury x1

Stage 19：Empusa x4；Red Empusa x1

Son of Sparda

Stage 20 （50k bonus）：Goliath

DH

Stage 21：Empusa x3；Green x2

Stage 22：Caina x2；Antenora x2

Stage 23：Pyrobat x8；Hellbat x1

Stage 24：Lusachia x1；Baphomet x2

Stage 25：Fury x1；Riot x2

Stage 26：Enraged Queen x1；Green x2

Stage 27：Proto x1；Scudo x2

Stage 28：Riot x1；Chaos x2

Stage 29：Qliphot Tentacle x3

Stage 30 （10k bonus）：1st wave：Caina x9 / 2nd wave：Antenorax6；Judeca x2

SoS

Stage 31：Pyrobat x3

Stage 32：1st wave：Hellbat x1 / 2nd wave：Empusa x5

Stage 33：Death Scissors x2；delayed Nobody x1

Stage 34：Pyrobat x3；Red Empusa x1

Stage 35：Hellbat x3；slight delay Hellbat x2

Stage 36：Caina x1；Green Empusa x2

Stage 37：Behemoth x1；slight delay Death Scissors x3

Stage 38：Qliphot Tentacle x4

Stage 39：1st wave：Pyrobat x3；2nd wave：Hellbat x2；3rd Wave：Death Scissors x2

Stage 40 （60k bonus）：Artemis

Stage 41 （arena change）：Baphomet x1；Empusa x4

Stage 42：Scudo x2；slight delay Empusa x6

Stage 43：Judeca x1；delayed Green Empusa x3

Stage 44：Chaos x2；slight delay Empusa Queen x1

Stage 45：Empusa x106；Fury x1

Stage 46：Nobody x3；Green Empusa x3

Stage 47：Antenora x3；Empusa Queen x1

Stage 48：Empusa x5；Behemoth x1

Stage 49：Riot x1；Green Empusa x2

Stage 50 （20k bonus）：Enraged Empusa Queen x3

Stage 51：Red Empusa x2

Stage 52：Caina x2；Pyrobat x1

Stage 53：Death Scissors x2 （normal spawn）；Lusachia x1

Stage 54：1st wave：Qliphot Tentacle x1 / Wave 2：Behemoth x3

Stage 55：Proto x1；Caina x3

Stage 56：Scudo x1；Baphomet x2

Stage 57：Proto x2

Stage 58：Scudo x2；Death Scissors x1 （normal spawn）

Stage 59：Proto x1；Qliphot Tentacle x6

Stage 60 （80k bonus）：Caveliere

Stage 61：Riot x4

Stage 62：Riot x2；Hellbat x1

Stage 63：Chaos x1；slight delay Baphomet x2

Stage 64：Antenora x2；Fury x1

Stage 65：Behemoth x1；Chaos x2

Stage 66：Qliphot Tentacle x6；Fury x1

Stage 67：Empusa Queen x1；Riot x3

Stage 68：Chaos x2；Nobody x1

Stage 69：Chaos x1；Green Empusa x2

Stage 70 （30k bonus）：Fury x3

Stage 71：Caina x2；Green Empusa x3

Stage 72：Antenora x3；Pyrobat x2

Stage 73：Empusa x8；Judeca x1

Stage 74：Caina x7；delayed Lusachia x1

Stage 75：Antenora x6；Behemoth x1

Stage 76：Judeca x1；Nobody x2；Caina x1 and Antenora x1 summoned by Judeca

Stage 77：Death Scissors x2 （normal spawn）；Caina x1

Stage 78：Antenora x1；Baphomet x2

Stage 79：1st wave：Proto x1；Judeca x2 / 2nd wave：Qliphot Tentacle x4

Stage 80 （90k bonus）：Malphas

Dante Must Die

Stage 81 （arena change）：Empusa x10

Stage 82：Antenora x4

Stage 83：1st wave：Riot x3；2nd wave：Chaos x2

Stage 84：Pyrobat x3；Green Empusa x4；delayed Hellbat x1

Stage 85：Nobody x1；Behemoth x1；Empusa Queen x1

Stage 86：Caina x2；Green Empusa x1

Stage 87：Proto x1；Riot x2

Stage 88：Fury x2

Stage 89：Qliphot Tentacle x10

Stage 90 （100k bonus）：King Cerberus

Stage 91：Red Empusa x3

Stage 92：Baphomet x2；Caina x10

Stage 93：Death Scissors x1 （normal spawn）；very small delay Death Scissors x2；very small delay Death Scissors x2

Stage 94：1st wave：Scudo x1；delayed Lusachia x2 / 2nd wave：Qliphot Tentacle x3

Stage 95：Empusa x1；Scudo x1；Caina x1；Pyrobat x1；spawn-on-kill Riot x1；spawn-on-kill Death Scissors x1

Stage 96：Chaos x1；Antenora x1；Baphomet x1；spawn-on-kill Nobody x1；spawn-on-kill Hellbat x1；Pyrobat x1

Stage 97：1st wave：Proto x1；slight delay Judeca；spawn-on-kill Behemoth x1；spawn-on-kill Empusa Queen x1；spawn-on-kill Lusachia x1；spawn-on-kill Fury x1 / 2nd wave：Qliphot Tentacle x3

Stage 98：Urizen 1 （ends on crystal break）

Stage 99：Urizen 2

Stage 100 （110k bonus）：Urizen 3 （drops green orbs）

Stage 101：Vergil

全關卡通關後：300k

來源：鬼泣吧
作者：skkkka